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What is a major side effect associated with lidocaine administration?

  1. Hyperglycemia

  2. Hypotension

  3. Hypertension

  4. Increased heart rate

The correct answer is: Hypotension

Lidocaine, an antiarrhythmic medication commonly used in clinical practice, can lead to hypotension as a major side effect. This occurs because lidocaine acts as a sodium channel blocker, which can affect myocardial conduction and contractility, potentially leading to a decrease in blood pressure. It can also cause vasodilation, further contributing to the drop in blood pressure. The effects of lidocaine on the cardiovascular system are vital for paramedics to understand, as they may need to monitor patients closely after administration. While other side effects may occur with lidocaine, such as central nervous system reactions or local anesthetic toxicity, hypotension is particularly significant in emergency settings, where maintaining hemodynamic stability is crucial. Understanding this side effect helps professionals anticipate and manage potential complications during patient treatment.